Recombinant SARS-CoV-2 nsp10 protein (His tag)
Species: SARS-CoV-2
Expression System: prokaryotic
Amino acid sequence: Ala1 – Gln139
Tag: N-terminal 6-His tag
Predicted molecular weight: 18 kDa
Type: recombinant protein
Conjugate: unconjugated
Recombinant SARS-CoV-2 nsp10 protein (His tag)
SDS-PAGE with Coomassie Blue (left) and Western blot with anti-His Ab (right) of SARS-COV-2 nsp10 (aa1-139), His Tag Recombinant Protein showing a band at approx. 18 kDa.
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Description
SARS-CoV-2 nsp10 is a small (139aa) protein involved in the replication and transcription of the viral RNA. Sequence of nsp10 shows high similarity with other pathogenic coronaviruses. Nsp10 binds to and stimulates the 3′-to-5′ exoribonuclease (nsp14) and the 2′-O-methlytransferase (nsp16). Because of its involvement in the formation of viral mRNA capping machinery it represents a prominent drug target.
Additional information
| FORM | Liquid |
|---|---|
| STORAGE | -20°C. Avoid freeze-thaw cycles. |
| STORAGE BUFFER | DEB buffer (8M urea, 200mM Na3PO4, 500mM NaCl; pH 4.0) |
| PURITY | Affinity purified |
| REFERENCES | Pribanić Matešić et al. Viruses 2022, 14(2), 443. |
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