Recombinant SARS-CoV-2 nsp7 protein (His tag)
Species: SARS-CoV-2
Expression System: prokaryotic
Amino acid sequence: Ser1 – Gln83
Tag: C-terminal 6-His tag
Predicted molecular weight: 10 kDa
Type: recombinant protein
Conjugate: unconjugated
Recombinant SARS-CoV-2 nsp7 protein (His tag)
SDS-PAGE with Coomassie Blue (left) and Western blot with anti-His Ab (right) of SARS-COV-2 nsp7 (aa1-83), His Tag Recombinant Protein showing a dominant band at approx.10 kDa.
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Description
SARS-CoV-2 nsp7 is a small protein (83aa) involved in the replication and transcription of the viral RNA. It forms a complex with nsp8 which acts as a primase for the viral RNA-dependent RNA polymerase (RdRp), nsp12. Nsp7/nsp8 complex is critical for viral polymerase activity. Nsp7 also interacts with nsp5, nsp9, and nsp13 including various host proteins involved in membrane trafficking, signaling, and transport.
Additional information
| FORM | Liquid |
|---|---|
| STORAGE | -20°C. Avoid freeze-thaw cycles. |
| STORAGE BUFFER | DEB buffer (8M urea, 200mM Na3PO4, 500mM NaCl; pH 4.0) |
| PURITY | Affinity purified |
| REFERENCES | Pribanić Matešić et al. Viruses 2022, 14(2), 443. |
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