VZV ORF57 encodes a poorly characterized protein of predicted 8 kDa molecular mass. Initial immunoprecipitation experiments using antibodies to ORF57 protein revealed a 6 kDa protein in the cytoplasm of infected cells that was dispensable for viral replication in cell culture. Later, we have observed a membrane associated localization of ORF57 as well as its localization in the Golgi-network. Based on performed analyses, it has presumed that the product of VZV ORF57 might play a role in virion morphogenesis. Our anti-VZV ORF57 antibody VZ 57.10 works in ELISA (on immunogen) and IF (on VZV infected cells) and each LOT is validated for Western blot (of VZV infected cell lysates) where it specifically recognizes a protein species of ~12 kDa in lysates obtained from VZV infected cells (described in J Virol. 2013 Jun;87(12):6943-54.).