Immediate-early 62 protein (IE62) is a homolog of herpes simplex type 1 (HSV-1) ICP4. These two proteins have conserved DNA bidnding domain,while not activation domain (J Virol 1993. 67: 4246-4251). IE62 is the major VZV transactivator and contains a potent N-terminal acidic activation domain (J Virol 1993. 67: 4474-4483). This protein is a tegument protein expressed in latency and required for the viral growth in vitro (J Virol 1992. 66: 359-366). Our anti-VZV62 antibody VZ 62N.05 works in ELISA (on immunogen), IF (on VZV infected cells) and each LOT is validated for Western blot of VZV infected cell lysates, where it gives a pattern as described in J Virol. 2013 Jun;87(12):6943-54.
Clone: VZ 62N.05
Catalog No.: HR-VZV-23
Host Species: Mouse
Reactivity: Varicella zoster virus
Antigen/Immunogen: The immunogen consisted of full length ORF62 protein and was produced in E.coli
Tested Applications: ELISA; WB
Varicella zoster virus
The immunogen consisted of full length ORF62 protein and was produced in E.coli
€120.00 – €500.00
|STORAGE||Long term -20 °C, short term +4 °C. Avoid freeze-thaw cycles.|
|LIGHT CHAIN TYPE||kappa|
|REFERENCES||Lenac et al., J Virol, 2013|
VZV ORF19 encodes a large, N-terminal subunit 1 of the viral ribonucleotide reductase, which together with the small subunit, encoded by the VZV ORF 18, forms the ribonucleotide reductase holoenzyme complex (RNR).