VZV ORF58 is located at the 3′ UL region of the Varicella Zoster Virus genome and encodes a 25 kDa protein with an unknown function. It is a nuclear phosphoprotein shown to be dispensable for viral replication in vitro (Yoshii et al., 2008, Journal of Virology). Our anti VZV ORF58 antibody VZ 58.01 works in ELISA (on immunogen), in IF (on VZV infected cells) and each LOT is validated for Western blot on VZV infected cell lysates where it gives a pattern as described in J Virol. 2013 Jun;87(12):6943-54.
Clone: VZ 58.01
Catalog No.: HR-VZV-19
Host Species: Mouse
Reactivity: Varicella zoster virus
Antigen/Immunogen: The immunogen consisted of full length ORF58 fused with MBP and was produced in E.coli
Tested Applications: ELISA; WB
Recommended Dilution: n/a
Varicella zoster virus
The immunogen consisted of full length ORF58 fused with MBP and was produced in E.coli
€200.00 – €700.00
|STORAGE||Long term -20 °C, short term +4 °C. Avoid freeze-thaw cycles.|
|LIGHT CHAIN TYPE||kappa|
|REFERENCES||Lenac et al., J Virol, 2013|
VZV ORF18 (UniProtKB – Q6QCN7) encodes a small subunit of the viral ribonucleotide reductase, which together with the large subunit, encoded by the VZV ORF19, forms the ribonucleotide reductase holoenzyme complex (RNR)
VZV ORF19 encodes a large, N-terminal subunit 1 of the viral ribonucleotide reductase, which together with the small subunit, encoded by the VZV ORF 18, forms the ribonucleotide reductase holoenzyme complex (RNR).