CD300c is an activating receptor expressed by leukocytes that belongs to the CD300 family of molecules (Borrego, Blood, 2013, 121(11): 1951–60). The CD300 family of receptors is a group of eight type-I membrane glycoproteins that harbor a single IgV-like extracellular domain and regulate a diverse array of immune processes. The human activating receptor CD300c has a short cytoplasmic tail, a negatively charged amino acid residue in the transmembrane region and the potential to to signal via adaptor molecules FcεRIγ and DAP12 (Clark GJ, Trends Immunol, 2009; 30(5):209-217). Our anti-CD300c antibody CMRF-2.13(08) works in ELISA (on immunogen) and FACS (as described in Lankry et al, J Immunol, 2010; 185;2877-2886).
Catalog No.: HR-Lympho-10
Host Species: Mouse
Antigen/Immunogen: The immunogen consisted of CD300c ectodomain fused to the hIgG1 Fc fragment and was produced from the supernatant of HEK 293T cells
Tested Applications: ELISA; FACS
Recommended Dilution: n/a
€200.00 – €700.00