Anti-human VSTM1 antibody
Clone: hVSTM1.07
Catalog No.: HR-Lympho-11
Host Species: Mouse
Reactivity: Human
Antigen/Immunogen: The immunogen consisted of hVSTM1 ectodomain fused to the hIgG1 Fc fragment and and was produced from the supernatant of HEK 293T cells
Tested Applications: ELISA, FACS
€200.00 – €1,500.00
Anti-human VSTM1 antibody
Overlay histogram showing CD14+ hPBMCs stained with 1:100 VSTM1.07 Ab (red line) and FITC-conjugated anti-mouse IgG. Isotype control antibody (black line) was mouse IgG used under the same conditions.
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Description
V-set and transmembrane domain containing 1 (VSTM1) encodes two main splicing isoforms, VSTM1-v1 and VSTM1-v2 (Guo, Cell Immunol 2012, 278: 136–142; Steevels, J Immunol. 2010;184:4741–8). VSTM1-v1 is a type I membrane molecule and is mainly expressed in human peripheral blood granulocytes and monocytes (Steevels, J Immunol. 2010;184:4741–8). VSTM1-v2 is a soluble protein that can promote the differentiation and activation of Th17 cells (Guo, Cell Immunol 2012, 278: 136–142). In addition, VSTM1 expression has been associated with rheumatoid arthritis and tumors (Wang, 2016, PLoS ONE 11(1); Zhou, 2016, Apoptosis 21(10):1179-90). Our anti-hVSTM1 antibody hVSTM1.07 works in ELISA (on immunogen) and in FACS (on human cells).
Additional information
| FORM | Liquid |
|---|---|
| STORAGE | Long term -20 °C, short term +4 °C. Avoid freeze-thaw cycles. |
| CONCENTRATION | 1 mg/mL |
| PURITY | Affinity purified |
| CLONALITY | Monoclonal |
| ISOTYPE | IgG1 |
| LIGHT CHAIN TYPE | kappa |
| REFERENCES | n/a |
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