Anti-human KIR2DS2 antibody
Clone: KIR2DS2-2.08
Catalog No.: HR-Lympho-06
Host Species: Mouse
Reactivity: Human
Antigen/Immunogen: The immunogen consisted of KIR2DS2 ectodomain fused to the hIgG1 Fc fragment and was produced from the supernatant of HEK 293T cells
Tested Applications: ELISA, FACS
€200.00 – €1,500.00
Anti-human KIR2DS2 antibody
Dot plot graph showing CD56+ hPBMCs stained with 1:100 KIR2DS2 2.08 Ab (red dots) and FITC conjugated anti-mouse IgG . Isotype control antibody (black dots) was mouse IgG used under the same conditions.
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Description
KIR2DS2 is an activating member of the killer cell Ig-like receptor (KIR) family (Parham, Nat. Rev. Immunol. 5: 201–214). KIRs are transmembrane glycoproteins expressed on natural killer cells that detect the major histocompatibility complex (MHC) class I on cells. KIR2DS2 contains two extracytoplasmic Ig-like domains and a short cytoplasmic tail that lacks inhibitory motifs and associates to KARAP/DAP12 polypeptides. DAP12 contains ITAM that are involved in the transduction of activating signals (Lanier, 1998, Nature 391: 703–707). Our anti-KIR2DS2 antibody KIR2DS2-2.08 works in ELISA (on immunogen) and in FACS (on human cells).
Additional information
| FORM | Liquid |
|---|---|
| STORAGE | Long term -20 °C, short term +4 °C. Avoid freeze-thaw cycles. |
| CONCENTRATION | 1 mg/mL |
| PURITY | Affinity purified |
| CLONALITY | Monoclonal |
| ISOTYPE | IgG1 |
| LIGHT CHAIN TYPE | kappa |
| REFERENCES | n/a |
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