PSG1 is the most abundantly expressed of the 11 different pregnancy-specific glycoproteins (PSGs) which are members immunoglobulin superfamily (Blois, Mucosal Immunol, 2014; 7:348–358). PSGs belong to carcinoembryonic antigen (CEA) family but differ from other CEA family members in that they are secreted rather than membrane-bound. Human PSGs are highly glycosylated proteins composed of an immunoglobulin (Ig) variable-like domain followed by constant-like domains (Zhou, Placenta 18, 491–501 (1997). These proteins are important in pregnancy and are involved in carcinogenesis.
Our anti-PSG1 antibody (PSG.11) works in ELISA (on immunogen), Western blot and IHC (of human tissues, as described in MAbs. 2016 Apr; 8(3): 491–500.).

