PSG1 is the most abundantly expressed of the 11 different pregnancy-specific glycoproteins (PSGs) which are members immunoglobulin superfamily (Blois, Mucosal Immunol, 2014; 7:348–358). PSGs belong to carcinoembryonic antigen (CEA) family but differ from other CEA family members in that they are secreted rather than membrane-bound. Human PSGs are highly glycosylated proteins composed of an immunoglobulin (Ig) variable-like domain followed by constant-like domains (Zhou, Placenta 18, 491–501 (1997). These proteins are important in pregnancy and are involved in carcinogenesis. Our anti-PSG1 antibody (PSG.11) works in ELISA (on immunogen), Western blot and IHC (of human tissues, as described in MAbs. 2016 Apr; 8(3): 491–500.).
Catalog No.: HR-Lympho-04
Host Species: Mouse
Antigen/Immunogen: The immunogen consisted of PSG1 ectodomain fused to the hIgG1 Fc fragment and was produced from the supernatant of HEK 293T cells
Tested Applications: ELISA; IHC; WB
Recommended Dilution: n/a
The immunogen consisted of PSG1 ectodomain fused to the hIgG1 Fc fragment and was produced from the supernatant of HEK 293T cells
ELISA; IHC; WB
€200.00 – €700.00
|STORAGE||Long term -20 °C, short term +4 °C. Avoid freeze-thaw cycles.|
|LIGHT CHAIN TYPE||kappa|
V-set and transmembrane domain containing 1 (VSTM1) encodes two main splicing isoforms, VSTM1-v1 and VSTM1-v2 (Guo, Cell Immunol 2012, 278: 136–142; Steevels, J Immunol. 2010;184:4741–8).
Human activating receptor natural-killer group 2, member D (NKG2D) is a 35 kDa type II transmembrane glycoprotein and a part of CD94/NKG2 family of C-type lectin-like receptors
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by <1-8% NK cells and subsets of CD8+ T cells (Melero et al., 1994, The Journal of Immunology, 152(4)).