Anti-ORF54 (VZV) antibody
Clone: VZ 54.08
Catalog No.: HR-VZV-35
Host Species: Mouse
Reactivity: Varicella zoster virus
Antigen/Immunogen: E.coli produced full lenght ORF54
Tested Applications: ELISA, WB
€200.00 – €1,500.00
Anti-ORF54 (VZV) antibody
Western blot Lysates of cells: a= uninfected cells b=VZV infected cells
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Description
The monoclonal antibody VZ 54.08 recognizes VZV ORF54.
VZV ORF54 assembles as a dodecamer and has a role in DNA packaging (UniProtKB – Q6QCK2). Its HSV-1 homolog is UL6. Visalli et al (J. Virol. July 2014 vol. 88 no. 14 7973-7986) showed that the VZV ORF54 is essential for cleavage and packaging of viral DNA. The ORF54 monomer has predicted molecular weight of 87 kDa and our monoclonal antibody shows a doublet band at around 90 kDa in Western blot.
Our anti-ORF54 antibody has been validated in ELISA (on immunogen) and in WB (VZV infected cell lysates) as described in J Virol. 2013 Jun;87(12):6943-54.
Additional information
| FORM | Liquid |
|---|---|
| STORAGE | Long term -20 °C, short term +4 °C. Avoid freeze-thaw cycles. |
| CONCENTRATION | 1 mg/mL |
| PURITY | Affinity purified |
| CLONALITY | Monoclonal |
| ISOTYPE | IgG1 |
| LIGHT CHAIN TYPE | kappa |
| REFERENCES | Journal of Virology (2013) 87, 6943–6954 |
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