ORF47 protein is a tegument protein which possesses a kinase activity (J Gen Virol 1994. 75 (Pt 2): 317-326, Virology 1992. 191: 9-18) and is a homolog of herpes simplex type 1 (HSV-1) UL13, human cytomegalovirus (hCMV) UL97 and Epstein Barr virus (EBV) BFLF4 protein kinases (J Virol 1989. 63: 450-455). This protein is essential for the T cell tropism (Proc Natl Acad Sci U S A 1998. 95: 11969-11974) and for VZV replication in immature dendritic cells (DC), but not in mature DC (Virology 2005. 337: 304-311). The ORF47 kinase was reported to form a complex with VZV IE62 (J Virol 2003. 77: 5964-5974). Our anti-VZV47 antibody VZ 47.01 works in ELISA (on immunogen), IF (on VZV infected cells) and each LOT is validated for Western blot of VZV infected cell lysates, where it gives a pattern as described in J Virol. 2013 Jun;87(12):6943-54.).

FORM	Liquid
STORAGE	Long term -20 °C, short term +4 °C. Avoid freeze-thaw cycles.
CONCENTRATION	1 mg/mL
PURITY	Affinity purified
CLONALITY	Monoclonal
ISOTYPE	IgG1
LIGHT CHAIN TYPE	kappa
REFERENCES	Lenac et al., J Virol, 2013

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