VZV ORF41 encodes a ~34 kDa protein that is packaged into the nucleocapsid core of the VZV virions together with protein products of ORFs 20, 21, 23, 33 and 40. By employing multiplex mRNA RT-PCR analysis, it has been shown that ORF41 belongs to the group of VZV genes latently expressed in trigeminal ganglia. Protein product of the VZV ORF41 plays a role in capsid morphogenesis by forming a 2:1 protein complex with capsid triplex subunit 1 thereby connecting nucleocapsid hexons and pentons in the VZV virions. Our anti-VZV ORF41 antibody VZ 41.01 works in ELISA (on immunogen) and each LOT is validated for Western blot of VZV infected cell lysates (described in J Virol. 2013 Jun;87(12):6943-54.).
Clone: VZ 41.01
Catalog No.: HR-VZV-16
Host Species: Mouse
Reactivity: Varicella zoster virus
Antigen/Immunogen: The immunogen consisted of full length ORF41 and was produced in E.coli
Tested Applications: ELISA; WB
Recommended Dilution: n/a
Varicella zoster virus
The immunogen consisted of full length ORF41 and was produced in E.coli
€200.00 – €700.00
|STORAGE||Long term -20 °C, short term +4 °C. Avoid freeze-thaw cycles.|
|LIGHT CHAIN TYPE||kappa|
|REFERENCES||Lenac et al., J Virol, 2013|
The ORF50 gene of the varicella-zoster virus (VZV) encodes glycoprotein M which is conserved among all herpesviruses. VZV gM is predicted to be an eight-transmembrane envelope glycoprotein modified with a complex N-linked oligosaccharide.
ORF48 encodes an alkaline nuclease (J Virol. 87: 11936-11938). ORF48 protein is homologous to herpes simplex type 1 (HSV-1) UL12, human cytomegalovirus (hCMV) UL98 and Epstein Barr virus (EBV) BGLF5.