The monoclonal antibody VZ40.1.03 recognizes VZV ORF40.

VZV ORF40, the major capsid protein, is a homomultimer that self-assembles to form an icosahedral capsid (UniProtKB – Q4JQT5). Its HSV-1 ortholog is UL19. Nagel et al (J. Virol. March 2011 vol. 85 no. 5 2276-2287) detected 10 VZV transcripts in latently infected human trigeminal ganglia in the following order of prevalence: ORF 63 (69%), ORF 29 (38%), ORF 4 (31%), ORF 62 (27%), ORF 11 (27%), ORF 68 (23%), ORF 40 (15%), ORF 43 (8%), ORF 41 (4%), and ORF 57 (4%). The ORF40 has predicted molecular weight of 115 kDa.

Our anti-ORF40 antibody has been validated in ELISA  (on immunogen) and WB (VZV infected cells lysates) as described in J Virol. 2013 Jun;87(12):6943-54.).

FORM	Liquid
STORAGE	Long term -20 °C, short term +4 °C. Avoid freeze-thaw cycles.
CONCENTRATION	1 mg/mL
PURITY	Affinity purified
CLONALITY	Monoclonal
ISOTYPE	IgG1
LIGHT CHAIN TYPE	kappa
REFERENCES	Journal of Virology (2013) 87, 6943–6954

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