No products in the cart.
Anti-MATp1 (MCMV) antibody
Clone: MAT GTG.01
Catalog No.: HR-MCMV-18
Host Species: Mouse
Reactivity: Murine cytomegalovirus
Antigen/Immunogen: His-tagged MATp1 produced in E.coli
Tested Applications: ELISA; IP; Proximity ligation assay (PLA); WB
€400.00 – €1,500.00
Anti-MATp1 (MCMV) antibody
Western blot analysis of MATp1 on uninfected cells, WT MCMV infected cells and ΔMAT/ΔMATp1 MCMV infected cells. Actin is shown as loading control and m04 as control of virus infection.
Available Options:
Description
The monoclonal antibody anti-MATp1 recognizes MCMV protein MATp1.
MATp1 is a 11-kDa protein that is encoded by the MCMV’s most abundant transcript (MAT). It is involved in major histocompatibility complex class I (MHC I) trafficking and immune evasion. Together with MCMV protein m04, MATp1 bind to MHC I molecules in the endoplasmic reticulum (ER) and helps m04/MHC I complex formation and its egress to the cell surface where this complex engages inhibitory Ly49 receptors in order to prevent NK cell activation and killing (J Exp Med 2019. 216(8):1809-1827; PLOS Pathogens 2013. 9:e1003611).
Our anti-MATp1 antibody has been validated in ELISA (on immunogen), WB (MCMV infected cell lysates), IP (MCMV infected cell lysates) and proximity ligation assay (MCMV infected cells) as described in J Exp Med 2019. 216(8):1809-1827.
Additional information
| FORM | Liquid |
|---|---|
| STORAGE | Long term -20 °C, short term +4 °C. Avoid freeze-thaw cycles. |
| CONCENTRATION | 1 mg/mL |
| PURITY | Affinity purified |
| CLONALITY | Monoclonal |
| ISOTYPE | IgG1 |
| LIGHT CHAIN TYPE | kappa |
| REFERENCES | J Exp Med 2019. 216(8):1809-1827.; PLoS Pathog 2013. 9: e1003611. |
Documents
Related products
Antibodies
€400.00 – €1,500.00
Antibodies
€400.00 – €1,500.00
Antibodies
€400.00 – €1,500.00
Antibodies
€400.00 – €1,500.00
Antibodies
€400.00 – €1,500.00
Antibodies
€400.00 – €1,500.00